Cellular uptake of a fluorescent vanadyl sulfonylcalix[4]arene.

نویسندگان

  • Carl Redshaw
  • Mark R J Elsegood
  • Joseph A Wright
  • Hugo Baillie-Johnson
  • Takehiko Yamato
  • Stephen De Giovanni
  • Anja Mueller
چکیده

Vanadyl bearing calix[4]arene ligands have undergone evaluation against several cell lines, and show varying degrees of toxicity. For vanadyl complexed to a sulfonylcalix[4]arene, monitoring of the strong blue fluorescence revealed slow uptake kinetics. The complex is exclusively found in the cytoplasm of the cells and uptake is not due to active endocytotic mechanisms.

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عنوان ژورنال:
  • Chemical communications

دوره 48 8  شماره 

صفحات  -

تاریخ انتشار 2012